Which way is the wind blowing?

The life science industry is always looking for ways to improve reliability and efficiency across the supply chain. New technologies for tracking and temperature logging hold great potential, but which to choose?
The implications of cloud-based IoT on temperature monitoring in the life science supply chain.

IoT on temperature monitoring

While the life science industry is celebrated for innovation in drug development, it is understandably conservative in its approach to early adoption of new technologies in areas such as logistics and distribution, where reliability and predictability of operations is critical.

Items such as temperature loggers continue to use hardware formats such as USB - universal, tried-and-tested and with relatively low failure rates. However, that reliability ceases to be a factor when users fail to upload the data to the system, causing gaps in the timeline which can lead to uncertainty of the shipping condition of the goods and ultimately questions on impact on patient safety, but also lack of data for insights that could improve supply chain efficiency. As an alternative, wireless technologies have come a very long way in a short time and their advantages in terms of efficiency, cost, and error-reduction now make them a compelling choice in many use cases.

Consider a typical example, where tracking of a pharma shipment is undertaken with a conventional logger. Upon the receipt of the shipment, a member of staff has to locate the logger, insert it into another device (typically a laptop, which might be in a different location) and manually upload the data. This physical process of uploading the data takes a significant amount of time per logger - multiply this by the number of shipments/packages and the hours add up. In addition, any system that relies on manual intervention has a greater potential for human error. People get distracted, can be insufficiently trained on a system, or be reliant on 3rd party software and hardware to transfer the data itself. Consider also that wireless systems allow for information such as temperature excursions to be automatically uploaded at key points in-transit, rather than just upon arrival at the ultimate destination - by which time there may be little that can be done.

While there are situations where a conventional logger is absolutely fit for purpose, it’s definitely the case that a wireless, automated solution has particular benefits; automated, reliable excursion reporting can contribute to reducing the costly waste of spoilt shipments, as well as eliminating delays in reporting while awaiting user intervention upon arrival.

So, of the most commonly used wireless protocols available, which is best? Kjell Runngren, Product Manager at TSS explains the options and their pros and cons:

“At first glance, when we look at RFID (Radio Frequency ID), we see many advantages.. It’s a trusted technology which is low cost, reliable, low power and has existed as a tried and tested standard for years. However, the need for specific, proprietary hardware scanners makes it an inflexible choice and not a global viable option.  

At the other end of the spectrum, cellular/GPS logging allows for real-time, continuous tracking of high-value shipments which, in some cases, can be invaluable. However, the vast majority of shipments don’t need real time - just an update at critical points where processes for intervention can be established along the supply chain. On the downside, cellular trackers are power-hungry, often a more expensive solution, and have regulatory restrictions when it comes to air travel and won´t last through longer missions or when stuck at customs for long time (they are, after all, mini-mobile phones).  

So that leaves Bluetooth. The most recent version (BLE, or Bluetooth Low Energy) is a quantum leap forward, building upon the reliability of previous generations but adding increased range and minimal power consumption. In addition, it is almost universally compatible, and the infrastructure is globally available. Every laptop, desktop, tablet or phone of the last decade will almost certainly come shipped with Bluetooth as standard.”

The upside is simple. Automated, no-touch tracking and upload to the cloud of key shipment data, such as temperature logs and location, with low cost, high reliability, and no need for expensive hardware or specialized personnel training.

Traditional monitoring equipment has served - and continues to serve - the industry well, but in a large number of cases it might well be time to cut the cord.

You may also be interested in

A collage illustrating three steps for clinical trials: vaccine vials, data analysis, and a healthcare professional.

3 steps to accelerate Decentralized trials & Release to patients

Seamless monitoring of direct-to-patient shipments within an end-to-end calculation engine enables a digital release in patient's homes. Site centric technology also allows for a decentralized and proactive approach, reducing waste. Furthermore, digitalizing temperature management end-to-end enables a faster release of products for all types of trials and creates a foundation for successful decentralized drives.
Read moreDownload Whitepaper
A clinical trial supply chain diagram over a stack of paperwork, representing the need for automation.

Future-Proofing Clinical Trials: How Sponsors Can Up-Scale Through Automation

At this year’s Clinical Trial Supply Europe event in Barcelona, TSS took center stage to discuss one of the most pressing challenges in clinical trial supply chains—temperature monitoring. Our Key Account Manager, Anita Leposa, highlighted how automation is revolutionizing temperature integrity management, reducing manual work, and ensuring compliance for global pharmaceutical sponsors.
Read moreDownload Whitepaper

Reducing excursion evaluation time from days to seconds

The question of how to speed up clinical trials is complicated, especially considering that many trial stages simply cannot be rushed in the interest of trial subjects and the general public. However, process improvements can go a long way.
Read moreDownload Whitepaper

You may also be interested in

Can You Rely on the Results from Your Clinical Trials?

The success of a clinical trial depends on the reliability of its data. Many investigational drugs are sensitive to temperature, and any temperature deviation can affect their quality and, in the worst case, patient safety. Automated and integrated temperature monitoring solutions help secure data quality, support compliance, and speed up the delivery of new medicines to patients.
Read more

Extending TempMonitor BLE to Ultra-Low Temperatures

Introducing the new TSS Dry Ice Probes, enginereed for accurate and GxP-compliant temperature monitoring down to –90°C. Available in two lengths for flexible setup — built to safeguard product integrity in every environment.
Read more

Subscribe to our newsletter

Sign up for our newsletter to receive all the latest TSS news and insights in temperature management solutions.